Successful transfer of longevity genes into mice: Scientist

Scientists have succeeded in transferring a gene linked to longevity from a hairless mouse into another mouse.

This is a breakthrough that has led to better health and longevity in mice.

Researchers have long studied hairless mice for their longevity and unusual resistance to related diseases.

According to research recently published in the journal Nature, a specific gene responsible for better cell repair in hairless mice was transferred to other mice.

As a result, the average lifespan of these mice increased by about five percent and overall health improved.

The scientists, including scientists from the University of Rochester in the US, say that these findings open the way to unraveling the mysteries of aging and the exciting possibilities of extending human lifespan.

Study co-author Vera Gorbunova says: ‘Our research provides proof of principle that unique longevity mechanisms evolved in long-lived mammals can be transferred to other mammals for longevity. can.’

Scientists have successfully transferred a gene into mice, which produces the high molecular weight hyaluronic acid (HMW-HA).

It’s a molecule that gives hairless mice exceptional resistance to cancer.

A previous study reported that hairless mice had 10 times more HMW-HA in their bodies than mice and humans, and when the molecule’s gene was removed from the mice’s bodies, their The cells are more likely to become cancerous.

In the new study, scientists genetically modified mice to produce the hyaluronan synthase-two gene found in hairless mice.

This gene is responsible for making the protein that produces the HMW-HA molecule.

Mice that had the same gene as hairless mice were better protected against both spontaneous tumors and chemical-induced skin cancers, the scientists said.

The researchers said that the overall health of the genetically modified mice also improved. They live longer than normal mice.

The study found that these mice also had less inflammation in different parts of the body, indicating slower aging and a relatively healthy digestive system.

According to the researchers, the new discovery could lead to new possibilities for improving aging and reducing inflammation in humans.

According to Andrey Sullivanov, another author of the study: ‘We have already identified molecules that slow down the degradation of hyaluronan and are testing them before clinical trials.’

Dr Sullivanov said: ‘We hope our results are the first but not the last example of how animal longevity techniques can be used to help humans live longer and healthier lives. ‘