Diabetes increases the risk of heart disease through “inflammation”… Especially dangerous in middle age when the aging process is accelerating.
Posted 2024.01.14 09:05 Views 8 Posted 2024.01.14 09:05 Modified 2024.01.14 03:22 Views 8
When you reach middle age, you have more thoughts and more stress. Stress influences the development of diabetes and heart disease through inflammation.
The link is metabolic syndrome. [사진=게티이미지뱅크]Research findings have shown that stress can be an important cause of metabolic syndrome through inflammation.
A research team from Ohio State University in the US found that stress is related to metabolic syndrome and that about 62% of the association was due to inflammation caused by stress.
People with metabolic syndrome have a higher risk of diabetes and heart disease. If you have three or more of five conditions, including excessive abdominal fat (abdominal fat), high blood pressure, low HDL cholesterol (good cholesterol), high fasting blood sugar, and high neutral blood fat (triglycerides) , we talk about metabolic syndrome. syndrome (insulin resistance syndrome). Genetics, lifestyle habits and various internal and external factors influence metabolic syndrome.
“Stress influences the development of metabolic syndrome through the body’s propensity to cause inflammation,” said Jasmit Hayes, associate professor of psychology and lead author of the study. “Stress is especially harmful to health after middle age, when aging accelerates,” she said. She emphasized: “If we manage stress, which is a psychological risk, we can reduce biological risk.”
The research team used data from 648 people (average age 52) who participated in a national survey titled “America’s Middle Ages” to build a statistical model to measure the relationship between inflammation, stress and metabolic syndrome. Additionally, information such as perceived stress reported by respondents, blood biomarkers for inflammation, and physical examination findings indicating risk factors for metabolic syndrome were used in the analysis.
To calculate the score that measures inflammation, the research team used biological substances such as interleukin 6 (IL-6), C-reactive protein, E-selectin and ICAM-1, which help recruit white blood cells during inflammation, and fibrinogen, a protein essential for the formation of blood clots A marker was used. Studies have shown that stress is actually closely related to metabolic syndrome, and statistical models have shown that inflammation explains 61.5% of the association.
“The link between stress and biological health is well established,” said Savanna Jurgens, graduate student and first author of the study. “However, there have been few studies that have specifically examined the involvement of inflammation in the relationship between stress and metabolic syndrome.” There are many studies showing that stress is related to inflammation, that inflammation is related to metabolic syndrome, and that stress is related to metabolic syndrome. However, research findings that comprehensively examine these three variables are rare.
Factors that negatively impact health include stress, lack of physical activity such as exercise, unhealthy eating habits, smoking, lack of sleep, low socioeconomic status, old age, and being female. Associate Professor Hayes said:Stress should not be considered only a mental health problem, that is, a psychological problem. Chronic stress really affects your body“It drew attention. The research team said there is a need for research that goes beyond observational studies and directly demonstrates causal relationships.
The results of this study (inflammatory biomarkers link perceived stress with metabolic dysregulation) were published in the journal Brain, Behavior & Immunity–Health.
Journalist Kim Young-seop
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2024-01-14 00:07:34
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