Is it okay to treat severe depression once or twice a year?

The effects of MRI-guided transcranial magnetic stimulation (TMS) last more than 6 months

Posted 2024.01.17 22:00 Views 0 Posted 2024.01.17 22:00 Modified 2024.01.17 17:22 Views 0

A new study has shown that when magnetic resonance imaging (MRI)-guided TMS is performed by accurately identifying the area of ​​stimulation, the effect is more pronounced and lasts more than six months. [사진= 게티이미지뱅크]One treatment for severe depression that does not respond to antidepressants is transcranial magnetic stimulation (TMS). It is a non-invasive treatment that improves depression by stimulating the prefrontal area of ​​the brain with magnetic energy fields in a conscious state to increase the secretion of serotonin and dopamine. However, the downside is that the effect only lasted 1 to 3 months.

A new study has shown that when magnetic resonance imaging (MRI)-guided TMS is performed by accurately identifying the area of ​​stimulation, the effect is more pronounced and lasts more than six months. This is what the health and medicine webzine ‘Health Day’ reports based on an article by British researchers published in Nature Medicine on the 16th (local time).

Patients who received MRI-guided TMS showed significant improvements in depression, anxiety, cognition, and quality of life for at least 6 months. A third had a 50% improvement in symptoms and a fifth showed a state of almost symptom-free remission.

Professor Richard Morris (psychiatry) from the University of Nottingham, UK, and lead author of the study, said: “Whereas these patients have not responded to two previous treatment attempts and have suffered from the disease for an average of 7 years , such a high response rate and persistence “What we saw was really encouraging,” he said.

Researchers conducted a clinical study in which 255 patients with treatment-resistant depression were recruited and completed a total of 20 TMS sessions. Patients underwent a TMI treatment that more accurately targeted the area of ​​the brain to be stimulated, combining precise magnetic induction through MRI with neuronavigation, a computerized tracking system. Professor Morris explained: “By personalizing the area of ​​stimulation using MRI and then stimulating the same area in each treatment session through neuronavigation, we reduce the variability of the stimulation in each treatment session.”

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The results of this clinical trial show that patients receiving MRI-guided TMS will only need one or two treatments a year, Professor Morris said. “The changes we observed were significant enough to not only reduce depressive symptoms, but also improve concentration, memory, anxiety and therefore quality of life,” he added.

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2024-01-17 13:01:08
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